
Overall Verdict: Best Methylfolate Supplement 1mg Methylfolate by envitamin
Methylfolate is one of the most important nutrients you can add to your daily routine. Now, more than ever, people are struggling to get enough active folate through food alone, and synthetic folic acid doesn’t work for everyone. This can lead to a range of unwanted health issues. Fortunately, a high-quality methylfolate supplement can give your body the active form of folate it needs to thrive.
But here’s the catch: not all methylfolate supplements are created equal. That’s why it’s critical to do your research (we’ve done it for you!) before choosing a product you may end up taking long-term.
Life can get busy, and it’s easy to overlook crucial nutrients like folate. A 1mg methylfolate supplement acts as an essential safety net, ensuring your body receives the activated form of folate it needs for DNA repair, cardiovascular health, energy, and mood support. Even on hectic days, it provides peace of mind that you’re fueling your body with the right form of this vital B-vitamin.
How Did We Rank?
We reviewed the top methylfolate supplements online and compared:
- Price
- Quality (purity, active form, and manufacturing standards)
- Efficacy (bioavailability and real-world results)
- Customer feedback
From there, we built a top 5 list to guide you toward the best 1mg methylfolate supplements available.
One thing we noticed: high-quality methylfolate is often from Calcium L-5 to enhance absorption and maximize benefits. By providing the active form of folate your body can use immediately, these supplements help support mood balance, healthy energy levels, and proper cell function.
Adding a 1mg methylfolate supplement to your daily routine can be a simple but powerful step toward better health. From supporting brain and heart health to aiding energy production and overall wellness, methylfolate delivers wide-ranging benefits. Just remember: supplements should complement a balanced diet and healthy lifestyle – not replace them.
And when it comes to your health, getting the optimal dosage, and picking the right product is always worth it. That’s why doing your research is key. With that in mind, check out our top methylfolate picks below!
Top 5 Methylfolate Supplements Of 2025

The 1mg methylfolate from envitamin is a clear winner when we tested it against others on the market. We loved the fact that it its priced fairly, and is the most absorbable form of methylated 5-MTHF (folate), Calcium L-5.
A+ Overall Best Methylfolate
Pure and potent methylfolate. This 1mg supplement is not only affordably priced, but highly rated by customers. Made with the active, methylated form (L-5-MTHF), it’s more absorbable and effective than standard folic acid.
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The 1mg methlflate from thorne is an excellent runner up when we tested it against others on the market. Its the same ingredient dosage as the envitmain one, but a little more expensive and unclear if it’s Calcium L5. A great substitute if envitamin is out of stock.
Great
Pure and potent methylfolate as well. Thorne is well known and highly rated by customers. Made with the active, methylated form (L-5-MTHF), it’s more absorbable and effective than standard folic acid.

Berry-flavored liquid sublingual form, designed for rapid absorption and increased bioavailability. It also includes methyl B12 as a cofactor.
Good
Expensive for what you get due to the poor absorption of the drops. Customers do like this brand and it comes recommended by various sources, however we dont see it beating our top 2 since the flavor isn’t the greatest.

After our rigorous tests we found it wasn’t worth the money. Overall too expensive, and the product itself was average with 800mcg (0.8mg) is under the optimal dosage. We thought that other options were better based on the pros and cons.
Good
It’s designed to support healthy methylation, cardiovascular function, and cellular repair. It also includes complementary B-vitamins and cofactors to enhance absorption and synergy for overall metabolic health. We think there is much better value elsewhere, which is why it did not make the top of our list. This product is only a good buy if others are unavailable.

Popular product but since it uses Metafolin we cant really recommend it.
Average
Overpriced and has too much vitamin B in it for us to recommend taking.